2F-Ketamine for Research
Introduction & Scientific Overview
2F-Ketamine, known chemically as 2-(2-fluorophenyl)-2-(methylamino)cyclohexan-1-one, is an arylcyclohexylamine compound. It belongs to the same chemical class as ketamine and PCP, featuring a cyclohexylamine core with an aryl substituent and a methylated amine group. This compound is structurally distinguished by a fluorine substituent on its phenyl ring, differing from ketamineâs chlorine atom at the same position.
Arylcyclohexylamines like 2F-Ketamine were originally studied during the exploration of dissociative anesthetics in the late 20th century. Though related compounds have clinical and research interest, 2F-Ketamine itself is primarily of scientific interest as a tool to investigate receptor interactions and molecular structure-activity relationships within this chemical class.
Chemical Specifications
| Specification | Detail |
|---|---|
| IUPAC Name | 2-(2-fluorophenyl)-2-(methylamino)cyclohexan-1-one |
| CAS Number | 111982-50-4 |
| Molecular Formula | C13H16FNO |
| Molecular Weight | 221.27 g/mol |
| Purity | >99% (HPLC) |
| Form | Crystalline powder |
| Storage | Store in a cool, dry place, away from light |
Potential Research Applications
2F-Ketamine is used in vitro predominantly to examine receptor binding affinity, especially in pharmacological profiling assays related to NMDA and other receptor interactions typical of arylcyclohexylamine compounds. It serves as a key compound in studying the structure-activity relationships (SAR) within this class of chemicals. Researchers also employ 2F-Ketamine as a reference standard in mass spectrometry and analytical chemistry due to its well-characterized chemical profile.
This compound facilitates enhanced understanding of how subtle chemical modifications impact receptor affinity and functional activity, making it valuable in mechanistic studies without implying any therapeutic or biological outcomes.
Quality Guarantee & Handling
All 2F-Ketamine provided is analytically validated with HPLC to confirm purity exceeding 99%. A batch-specific Certificate of Analysis (CoA) accompanies each shipment to ensure traceability and quality assurance.
Researchers must always wear appropriate personal protective equipment (PPE), including gloves and lab coats, when handling the material to ensure safety.
INTENDED USE & WARNING:
This product is strictly for laboratory research use by qualified personnel. It is not intended for human or animal consumption or for diagnostic or therapeutic purposes. The buyer assumes all responsibility for handling and legal compliance. By purchasing, you confirm adherence to all relevant laws and that you are over 18 years of age.
Why Source Your Research Chemicals from Us?
Verified Purity: Every compound undergoes rigorous third-party analytical testing.
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This information is compiled to meet research compliance and educational standards focusing on chemical and mechanistic insights, supporting scholarly and analytical use of 2F-Ketamine in the laboratory environment.

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