DeschloroKetamine (DCK) for Research

Introduction & Scientific Overview

DeschloroKetamine (IUPAC name: 2-(methylamino)-2-phenylcyclohexan-1-one) is an arylcyclohexylamine compound structurally related to ketamine but lacking the chlorine atom, which distinguishes it chemically. It contains a cyclohexanone ring bonded to a phenyl group and a methylamino side chain, enabling selective interaction with the NMDA receptor’s phencyclidine binding site. DCK exists as a racemic mixture with chiral enantiomers, among which the S-enantiomer exhibits greater receptor affinity.

DCK emerged within the designer drug market as a dissociative with pharmacodynamics and behavioural profiles similar to ketamine but with a slightly longer duration of effect. It remains primarily a research chemical studied for its molecular pharmacology and receptor interactions.

Chemical Specifications

Potential Research Applications

DeschloroKetamine is used in vitro to investigate NMDA receptor antagonism through non-competitive inhibition, facilitating studies on synaptic plasticity, memory formation mechanisms, and related pharmacological effects. It supports structure-activity relationship (SAR) analyses within dissociative compounds and is employed in profiling ligand-receptor interactions.

Its robust receptor activity and molecular characteristics make it invaluable for elucidating NMDA receptor dynamics and glutamatergic signaling pathways.

Quality Guarantee & Handling

Each batch of DCK undergoes stringent high-performance liquid chromatography (HPLC) testing to ensure >99% purity. A detailed Certificate of Analysis is provided to confirm quality and batch identity.

Personal protective equipment (PPE) such as gloves and lab coats is mandatory during handling to maintain safety and prevent contamination.

INTENDED USE & WARNING:
This compound is strictly intended for qualified laboratory research. It is not for human or animal consumption, therapeutic, or diagnostic use. Responsibility for safe handling and legal compliance rests with the purchaser. Confirmed legal age (18+) required.

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• Verified Purity: All batches undergo third-party analytical verification.

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This comprehensive, compliance-focused profile assists researchers in the safe and effective study of DeschloroKetamine’s pharmacological and receptor-binding properties.