3-Hydroxyeticyclidine (3-HO-PCE) for Research

Introduction & Scientific Overview

3-Hydroxyeticyclidine (3-HO-PCE), chemically described as 3-(1-(ethylamino)cyclohexyl)phenol, is a synthetic dissociative compound belonging to the arylcyclohexylamine class. It is structurally related to eticyclidine (PCE) and shares homology with 3-MeO-PCE, distinguished by a hydroxy group at the 3-position of the phenyl ring.

This compound acts as an antagonist at the N-methyl-D-aspartate (NMDA) receptor, inhibiting glutamate neurotransmission, which is a key target in dissociative pharmacology. While it has been studied to a limited extent, 3-HO-PCE is primarily of interest for research into receptor mechanisms and structure-activity relationships, without therapeutic implication.

Chemical Specifications

Potential Research Applications

3-HO-PCE is used in vitro for receptor binding studies focusing on NMDA receptor antagonism and exploring the pharmacological profile of dissociative arylcyclohexylamines. It facilitates research into molecular interactions at glutamatergic pathways and elucidation of structure-activity relationships within this compound class. Analytical chemistry and mass spectrometry applications also benefit from 3-HO-PCE as a reference compound.

Quality Guarantee & Handling

The product’s purity is verified by HPLC analyses confirming >99% purity with each batch accompanied by a Certificate of Analysis to assure quality and batch traceability.

Researchers are advised to employ standard laboratory safety protocols, including the use of personal protective equipment (PPE) such as gloves and lab coats while handling.

INTENDED USE & WARNING:
This chemical is sold exclusively for qualified laboratory research. It is not intended for human or veterinary use, consumption, or therapeutic application. Responsibility for compliance with local laws and safe handling resides with the purchaser. Confirm that the user is over 18 years of age.

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This formal profile supports compliant, informed use of 3-HO-PCE powder in scientific research focused on dissociative mechanisms and receptor pharmacology.