Buy Pagoclone Pellets 10mg For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
What is Pagoclone?
Pagoclone is a nonbenzodiazepine anxiolytic drug from the cyclopyrrolone family, structurally distinct from benzodiazepines but with similar anxiolytic effects. It acts as a selective modulator of GABA-A receptors, facilitating inhibitory neurotransmission in the central nervous system. Used primarily in research to explore anxiety mechanisms and GABA receptor pharmacology, Pagoclone exhibits anxiolytic properties with reduced sedative and muscle relaxant side effects compared to traditional benzodiazepines. In research contexts, Pagoclone pellets typically contain 10 mg of the active pharmaceutical ingredient formulated for controlled laboratory studies. This compound is intended strictly for research use and not approved for human or veterinary application.
Technical Information of Pagoclone Pellets 10mg
| Property | Details |
|---|---|
| CAS No | 133737-32-3 |
| Alternate Names | RP 59037; IP 456; CI-1043; 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)isoindolin-1-one |
| Chemical Formula | C23H22ClN3O2 |
| IUPAC Name | 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-2,3-dihydro-1H-isoindol-1-one |
| Molecular Weight | 407.89 g/mol |
| Smiles | CC(C)CCC(=O)CC1N(C(=O)C2=CC=CC=C12)C1=NC2=C(C=CC(Cl)=N2)C=C1 |
| Melting Point | Data not definitively available |
| Boiling Point | Approximately 582 ± 50 °C (predicted) |
| Long Term Storage | Store at -20°C in airtight container |
| Form | Pellets (10 mg) |
| Purity | ≥98% (verified by HPLC) |
Typical Research Applications of Pagoclone Pellets 10mg
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Studies on anxiolytic mechanisms via selective GABA-A receptor modulation
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CNS pharmacology research focusing on nonbenzodiazepine receptor interactions
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Behavioral and biochemical studies in animal models of anxiety
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Investigation of receptor pharmacodynamics and neuropharmacokinetics
Safety and Handling Information for Pagoclone Pellets 10mg
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Use personal protective equipment (PPE) such as gloves, lab coat, and eye protection
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Handle in a well-ventilated laboratory or under a fume hood to avoid dust and particulate inhalation
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Avoid ingestion, inhalation, or skin contact; wash hands after handling
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Store pellets in tightly sealed containers away from moisture and heat
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Follow institutional and local guidelines for disposal of chemical research substances
Ordering and Shipping Summary for Pagoclone Pellets 10mg
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Available from licensed chemical and pharmaceutical research suppliers
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Supplied as 10 mg pellets for precise dosing in experimental protocols
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Shipping compliant with relevant chemical transport regulations, typically via courier services with appropriate documentation
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Purchase restricted to qualified research institutions or entities
Storage Conditions for Pagoclone Pellets 10mg
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Recommended storage at -20°C in airtight containers to maintain stability
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Avoid exposure to light, moisture, and heat to prevent degradation
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Follow supplier-specific storage guidelines if provided
Alternatives to Pagoclone Pellets 10mg
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Other cyclopyrrolone family compounds with anxiolytic activity
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Benzodiazepines and other GABA-A modulators for comparative receptor studies
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Nonbenzodiazepine anxiolytics with differing receptor profiles such as zolpidem or eszopiclone
FAQ About Pagoclone Pellets 10mg
Q: Is Pagoclone approved for clinical use?
A: No. Pagoclone is primarily used for research purposes and is not approved for human or veterinary use.
Q: What purity is guaranteed for Pagoclone pellets?
A: Purity is guaranteed at ≥98%, confirmed through HPLC analysis.
Q: How should Pagoclone pellets be stored?
A: Store in dry conditions at -20°C in an airtight container, protected from light and moisture.
Q: What types of studies is Pagoclone used for?
A: It is typically used in pharmacological and behavioral research on anxiety and CNS receptor function.
Call to Action
For reliable, high-purity Pagoclone Pellets 10mg to support your neuroscience and pharmacological research, contact your licensed supplier today. Ensure all handling and experimental protocols comply with institutional safety and use guidelines.

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The reagent arrived quickly, and its purity ensured reliable results in our complex biochemical assays.
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A highly effective reagent for complex research applications. We are very satisfied with its performance.
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Top-quality products and excellent customer service.
Emma Moore (verified owner) –
The compound showed excellent solubility and reactivity in our assays, making it ideal for our research needs.