O-DSMT Powder (O-Desmethyltramadol) For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

What is O-DSMT Powder

O-DSMT (O-Desmethyltramadol), also known as desmetramadol or M1, is the main active metabolite of tramadol. It functions as a potent μ-opioid receptor agonist, providing significantly stronger analgesic effects than the parent drug. In research contexts, O-DSMT powder is used for studying opioid pharmacology, analgesia mechanisms, metabolic pathways, and receptor binding characteristics. Its high purity powder form enables accurate dosing for preclinical studies.

Technical Information of O-DSMT Powder

Typical Research Applications

• Opioid receptor pharmacology and analgesic effect research

• Metabolic and pharmacokinetic profiling of tramadol metabolites

• Central nervous system studies on pain and nociception

• Toxicology and receptor binding mechanism investigations

• Pharmacodynamic analyses in preclinical models

Safety and Handling Information

• Use appropriate personal protective equipment including gloves and eye protection

• Conduct research in ventilated labs or fume hoods

• Avoid exposure via ingestion, inhalation, or skin contact outside approved protocols

• Dispose of all waste according to institutional safety regulations

• Exclusively for research purposes, not for human or veterinary use

Ordering & Shipping Summary

O-DSMT powder is supplied by certified vendors in secure, tamper-proof packaging. Shipment is regulated and limited to qualified research laboratories.

Storage Recommendations

Keep powder in airtight containers stored away from light, moisture, and heat at recommended temperatures (2–8°C) to ensure stability.

FAQ About O-DSMT Powder

Q: How potent is O-DSMT compared to tramadol?
A: O-DSMT is 2–4 times more potent and has a higher affinity for the μ-opioid receptor than tramadol.

Q: What purity level is typical?
A: Research-grade O-DSMT powder is typically ≥98% pure.

Q: What fields utilize O-DSMT?
A: Opioid receptor pharmacology, analgesic research, metabolism studies, and CNS pharmacodynamics.

Q: How should O-DSMT powder be stored?
A: In cool, dry, dark conditions in sealed containers to preserve integrity.

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